Never the words ‘computer virus’ had as much sense that today ‘ hui. Oxford researchers come to take a new step in the simulation of life.
They have created a computer model of the virus of influenza, or rather an influenza virion. The goal is to better understand how the virus (the true) manages to survive in different environments from one season to another. With this computer model, researchers can study how reacts virus different liquid and at different temperatures. Tests ‘ in silico ‘ that can lead to infinity… without risk of infection.
A digital virus to test ‘In Silico’ to infinity
Research come to be unveiled by researchers at Oxford University at the annual conference of society of Biophysics who held the week last in Baltimore.
They fought has a unique computer simulation. They have fully modeled the outer of the influenza A virus (that is called a virion) and plunged it into a drop of water. The simulation was used to observe the behavior of the virus with a precision that it is difficult to obtain in classical experimentation at the macroscopic level. 300 nanoseconds, the diameter of the virion has increased from 73 to 59 nanometers.
One can imagine that will be able to understand like this what is the behavior of the virus of the flu when he finds himself plunged into a river and put in the presence of anti-virals components from the effluents of the human population.
The computer model has been developed by relying on various experimental measurements, since the crystallography to x-ray spectroscopy nuclear magnetic resonance, electron cryo-Microscopy Imaging, of studies of virus lipodimiques. This computer model is freely accessible to all researchers wishing to enrich it in turn. It will then allow them to virtually immerse this virus in all kinds of substances to observe the behavior.
Translation : Bing Translator
“Nothing to Sneeze at: A Full-Scale Computational Model of the Human Influenza Virion”, Biophysical Journal, January 27, 2015